Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is an inflammatory disease of the liver that results in immune mediated destruction of liver cells that can result in cirrhosis, liver failure, and even death. AIH can present as an acute fulminant event or insidiously over many years, however diagnosis and treatment implementation can be delayed because of complex clinical presentations. Epidemiologic reports have solidified the observation of a female predominance, yet AIH can present in all ages and ethnic populations. Limited data regarding prevalence of AIH has estimated between 50 and 200 cases per 1 million among Caucasians from Western Europe and North America.

Blood tests to diagnose AIH/Autoimmune hepatitis include the following tests:

ANA Screen, IFA, with Reflex to Titer and Pattern; Mitochondrial Antibody with Reflex to Titer; Actin (Smooth Muscle) Antibody (IgG); Liver Kidney Microsome (LKM-1) Antibody (IgG)

 

Leave a Reply